Hver gang et GABA-molekyl binder seg til en reseptor som også har et benzodiazepin bundet til seg, vil kloridkanalen åpne seg oftere og slippe inn mer negativ ladning. Resultatet er en kraftig forsterkning av den naturlige bremseeffekten, som fører til en utbredt demping av aktiviteten i de delene av hjernen som er involvert i angst, frykt og ur

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